Organisation of Mycobacterium leprae mce operon and expression of mce genes in leprosy patients
نویسندگان
چکیده
منابع مشابه
Analysis of expression profile of mce operon genes (mce1, mce2, mce3 operon) in different Mycobacterium tuberculosis isolates at different growth phases
BACKGROUND & OBJECTIVES Mycobacterium tuberculosis (M. tuberculosis) has four homologous mammalian cell entry (mce) operons (mce1-4) that encode exported proteins and have a possible role in the virulence mechanism of this pathogen. The expression of mce operon is considered to be complex and not completely understood. Although expression of mce operon at different in vitro growth phases has be...
متن کاملDifferent methods, different wilds: Evaluating alternative mappings of wildness using fuzzy MCE and Dempster-Shafer MCE
1 Department of Geography, University of Leicester, Leicester, LE1 7RH, UK, Tel +44 (0)116 252 3812, Fax +44 (0)116 252 3854, 2 School of Geography, University of Leeds, Leeds, LS2 9JT 3 International Institute for Applied Systems Analysis, Schlossplatz 1, A-2361, Laxenburg, Austria Tel +43 (0)2236 807 0, Fax: +43 (0)2236 71 313 4 Centre for Mountain Studies, Perth College-UHI, Perth, PH1 2NX, ...
متن کاملAnalysis of expression profile of mammalian cell entry (mce) operons of Mycobacterium tuberculosis.
The sequencing of the complete genome of M. tuberculosis H37Rv has resulted in the recognition of four mce operons in its genome by in silico analysis. In an attempt to understand the significance of the redundancy of mce operons, we analyzed the expression profile of mce operons after different periods of growth in culture as well as during in vivo infection. Our results strongly suggest that ...
متن کاملVNTR typing of Mycobacterium leprae in South Indian leprosy patients.
OBJECTIVES To study the suitability, stability and diversity of short tandem repeat (STR) genomic markers to elicit strain variation in the Mycobacterium leprae isolates within leprosy patients from Andhra Pradesh and Tamil Nadu states in South India. MATERIALS AND METHODS Slit skin smear (SSS) samples were collected from lesions and various body sites of newly diagnosed leprosy patients. The...
متن کاملGenetic diversity of mycobacterium leprae isolates from Brazilian leprosy patients.
INTRODUCTION Leprosy is a chronic disease caused by infection with Mycobacterium leprae, an obligate intracellular parasite. A problem in studying the transmission of leprosy is the small amount of variation in bacterial genomic DNA. The discovery of variable number of tandem repeats (VNTRs) allowed the detection of strain variation in areas with a high prevalence of leprosy. Four genotypes of ...
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ژورنال
عنوان ژورنال: International Journal of Advanced Biotechnology Research
سال: 2019
ISSN: 2249-3166
DOI: 10.37622/ijabr/9.1.2019.13-24